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Proceedings of the National Academy of Sciences  ·  21 October 2026  ·  From issue 55

C1ql2 gates stress vulnerability by regulating microglia-mediated synaptic pruning in the BLA-vHPC circuit

In mice, losing a protective brain gene let extra brain connections build up and raised anxiety.

Chun-Yan Wang, Wei-Zhu Liu et al.

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