Science Advances · 16 October 2026 · From issue 53

Immune biomarkers of response and resistance to ipilimumab and nivolumab in metastatic castration-resistant prostate cancer

A low dose immune drug combo matched higher doses but caused fewer side effects in prostate cancer.

Apostolia M. Tsimberidou, Christopher R. Cabanski et al.

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Also in issue 53 15 papers

A custom probe tool found bird flu and human flu genes in real sewage samples.
Nature Communications
In fruit fly larvae, single dopamine nerve cells can teach, store memory, and control movement together.
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In a Nebraska flood model, warming did not make floods bigger or more frequent overall.
Geophysical Research Letters
Total intake of heavily processed food was not linked to colon cancer risk.
PLOS Medicine
A liquid's memory of a trapped bead let scientists pull out extra energy from it.
Nature Physics
A new catalyst lets seawater make hydrogen fuel for over 2,450 hours without breaking down.
Nature Communications
Special salt additives made water filters thinner, stronger, and better at blocking salt.
Nature Communications
Touching a bleached coral to a healthy relative for days lets it fully recover its lost algae.
Science Advances
In a math model, heavy particles make an atmosphere's self-balancing electric field stronger.
The Astrophysical Journal
US states with higher pathogen levels have fewer interracial marriages and more restrictive dating preferences.
PNAS Nexus
A heat imbalance score predicts how well birds feed chicks and where species can live.
Proceedings of the National Academy of Sciences
Cities picked similar green ideas, like car-free zones, but for very different underlying reasons.
Proceedings of the National Academy of Sciences
A new method nearly doubled how many topics AI models can be steered toward.
Proceedings of the National Academy of Sciences
Some volcano magma gets up to half its magnesium from deep, wet rock near a sinking ocean plate.
Science Advances