Nature Communications · 11 October 2026 · From issue 50
Time-lapse RESOLFT nanoscopy empowered by deep learning
A computer program lets cell microscopes use far less damaging light and film much longer.
Guillaume Minet, Anirban Ray et al.
Powerful microscopes can zoom in on tiny parts of living cells, but the bright light needed often damages the cells before long movies can be made. A computer program can now clean up dim, noisy images and fill in gaps from faster scans. This lets scientists use 10 times less light per picture and record for up to 5 times longer, or film 4 times faster with fewer errors.
The improvement in how long cells can be filmed without damage from microscope light.
Lab cell imaging only, no human or animal testing shown.
Integrity screen: passed (3 checks) Checked 12 October 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (Nature Communications). Read the source
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