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In this issue 15 papers · 5 free

01 Proceedings of the National Academy of Sciences Stress-inducible WASF3 regulates brain metabolism and cognitive function Free
02 Nature Energy Structural improvements to address energy poverty had most substantial thermal comfort and health effects Free
03 Nature Communications Evaluation of vaccine-induced anti-lipopolysaccharide antibodies against clinically relevant Klebsiella pneumoniae strains to inform vaccine design Free
04 Nature Communications NK cells engineered with a chimeric antigen receptor delay HIV rebound and reshape HIV reservoir composition Free
05 The Astrophysical Journal Evolution of the High-energy Excess in Swift J1727.8-1613 during Its 2023 Flare State Free
06 Nature Chemistry Synthesis and isolation of stable oxoboranes Subscribers
07 Physical Review Letters Real-Space Imaging of Thomson Charge Configurations in Superfluid Helium Nanodroplets Subscribers
08 Nature Communications Early-life bovine respiratory virome analysis reveals phage-driven adaptation and cross-host evolutionary signatures Subscribers
09 Proceedings of the National Academy of Sciences Mechanically driven grain refinement in Mo by nanoindentation pop-ins: A case of transient instability Subscribers
10 Proceedings of the National Academy of Sciences Recognition-dependent activation of the Arabidopsis RRS1-R/RPS4 TIR-NLR immune receptor pair Subscribers
11 Nature Medicine Persistent and compartmentalized T cell immunity in ALS Subscribers
12 eLife A GCN1-independent activator of the kinase GCN2 Subscribers
13 eLife Light-entrained chromatin priming poises rapid metamorphosis in a marine sponge Subscribers
14 eLife Mid-zone hepatocytes trade proliferation for survival via Atf4-Chop axis in early acute liver injury Subscribers
15 PLOS Biology Tolerance measured at one developmental stage mispredicts climate resilience in an animal with a complex life cycle Subscribers

The papers Read free

Proceedings of the National Academy of Sciences·27 October 2026

Abu M. Syed, Jin Ma et al.

In mice, a stress protein weakens brain energy use and hurts memory and learning.

A protein called WASF3 builds up when cells are stressed. In mice, too much of it in a brain area used for memory caused brain cells to switch to a weaker energy system. This made the mice learn less well. Mice with no WASF3 kept using the stronger energy system and learned normally even under stress.

What it could change A stress protein in mouse brains cuts energy use and worsens learning, while removing it protects memory.

Shows a possible brain mechanism behind "brain fog" in chronic fatigue syndrome, tested only in mice.

Mouse study only, no human brain data yet.

Integrity screen: passed (3 checks) Checked 28 October 2026. Abu M. Syed, Jin Ma et al., Stress-inducible WASF3 regulates brain metabolism and cognitive function Read the source

Nature Energy·27 October 2026

Beverley A. Searle, Lucie Middlemiss et al.

Fixing homes and giving steady cash aid helped poor households stay warm and healthy.

Fixing a home's structure gave the biggest boost in warmth and health for people who struggle to pay for heating. This included things like insulation or better heating systems. Steady money support also helped health and energy habits. But when payments stopped and started, people's living conditions went up and down too.

What it could change Fixing a home's structure helped more than small upgrades or advice for warmth and health.

Based on tracking real households in six cities, not a controlled experiment.

Six cities, no controlled trial, so other causes are possible.

Integrity screen: passed (3 checks) Checked 30 October 2026. Beverley A. Searle, Lucie Middlemiss et al., Structural improvements to address energy poverty had most substantial thermal comfort and health effects Read the source

Nature Communications·27 October 2026

Robert Lawrence, Nathalie Karaky et al.

In lab tests, one antibody type killed most germ strains that cause newborn blood infections.

A vaccine ingredient can kill many strains of a dangerous newborn infection germ, a lab study shows. The germ, called Klebsiella pneumoniae, causes serious blood infections in babies and resists many antibiotics. Scientists tested antibodies made against one surface marker on 146 germ samples covering 17 different strains. Some strains died easily, some died sometimes, and some did not die at all, even though a different kind of antibody could still kill them.

The number 146 bacteria samples, 17 strain types

The number of newborn-sepsis bacteria samples tested for antibody killing in this lab study.

Lab dish test only, no human or animal data yet.

Integrity screen: passed (3 checks) Checked 28 October 2026. Robert Lawrence, Nathalie Karaky et al., Evaluation of vaccine-induced anti-lipopolysaccharide antibodies against clinically relevant Klebsiella pneumoniae strains to inform vaccine design Read the source

Nature Communications·27 October 2026

Yuan Shi, Izra Abbaali et al.

In mice, engineered immune cells delayed HIV's return and shrank the variety of virus that came back.

Engineered immune cells slowed the return of HIV after treatment stopped in mice. Scientists built natural killer cells with an added sensor that spots a hidden marker on HIV-infected cells. The cells hunted and killed infected cells in lab dishes. In mice, they also cut the number of virus types that came back and pushed the leftover virus into harder-to-wake hiding spots.

What it could change Engineered immune cells cut the number and spread of HIV strains that returned after treatment stopped, in mice.

Shows a lab and mouse result, not a proven treatment for people.

Humanized mice only, no human safety or efficacy data yet.

Integrity screen: passed (3 checks) Checked 28 October 2026. Yuan Shi, Izra Abbaali et al., NK cells engineered with a chimeric antigen receptor delay HIV rebound and reshape HIV reservoir composition Read the source

The Astrophysical Journal·27 October 2026

Xiao Fan, Bei You et al.

In a black hole system, extra high-energy light came from fast-kicked electrons, not just heat.

A black hole system gave off extra high-energy light during a bright flare in 2023. This light could not be explained by normal slow heating alone. Scientists found the extra light came from electrons getting kicked to very high speeds. At the same time, three blobs of material shot out along a jet from the black hole.

The number 2.08 to 2.61

The range of photon indices measured for the extra high-energy light during the flare.

One black hole system, one flare event studied.

Integrity screen: passed (3 checks) Checked 28 October 2026. Xiao Fan, Bei You et al., Evolution of the High-energy Excess in Swift J1727.8-1613 during Its 2023 Flare State Read the source

10 more papers are in the full issue.

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Nature Chemistry·27 October 2026

Lukas Lubczyk, Christian Markl et al.